How Does Menopause Change Your Skin?
Estrogen decline during menopause causes: 30% collagen loss in the first 5 post-menopausal years, reduced sebum production (drier skin), decreased hyaluron...
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Estrogen decline during menopause causes: 30% collagen loss in the first 5 post-menopausal years, reduced sebum production (drier skin), decreased hyaluron...
Dehydrated skin appears dull, rough, with more visible fine lines. Dehydration reduces skin elasticity (the pinch test: dehydrated skin takes longer to bou...
UV exposure (tropical and high-altitude climates): accelerated photoaging. Dry climates: chronic dehydration and barrier stress. Humid climates: better hyd...
UVA penetrates to the dermis → generates reactive oxygen species (ROS) → ROS activate transcription factor AP-1 → AP-1 upregulates MMP production → MMPs de...
Retinol is converted in the skin: retinol → retinaldehyde → all-trans retinoic acid (tretinoin), the active form. Retinoic acid binds to nuclear receptors ...